Naruto EP98 - Tsunade's Warning: Ninja No More!

Upon arriving in Konoha, preparations are made to formally put Tsunade into office, though she is largely uninterested in formalities and leaves the task to her new assistants. She makes her rounds in the Konoha hospital, healing Kakashi Hatake and Sasuke of the damage done to their minds by Itachi's Tsukuyomi. When examining the wounds to Rock Lee's body, Tsunade discovers that the damage to his spine is too extensive, even for her, to heal with certainty. She advises Lee to give up on his dreams of being a ninja, citing that there is only a 50% chance that he will survive the operation.

(Source: Wikipedia)

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